Colchicine is considered to act against the inflammatory response to urate crystals, by possibly inhibiting the migration of granulocytes into the inflamed area. Other properties of colchicine, such as interaction with the microtubules, could also contribute to the operation. Onset of action is approximately 12 hours after oral administration and is maximal after 1 to 2 days.

ATC Classification

Colchicine derivatives
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products
M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AC Preparations with no effect on uric acid metabolism

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