Cefotaxime

Cephotaxime

Therapeutic Indications

Cefotaxime is indicated for:

Infections of genitourinary system

Irrespective of gender only Newborns (0 - 40 days old) , Infants (40 days - 1 year old) , Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Treatment 2: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Intra-abdominal infections

Irrespective of gender only Newborns (0 - 40 days old) , Infants (40 days - 1 year old) , Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Treatment 2: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Infections of the lower respiratory tract

Irrespective of gender only Newborns (0 - 40 days old) , Infants (40 days - 1 year old) , Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Treatment 2: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Endocarditis

Irrespective of gender only Newborns (0 - 40 days old) , Infants (40 days - 1 year old) , Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Treatment 2: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Sepsis

Irrespective of gender only Newborns (0 - 40 days old) , Infants (40 days - 1 year old) , Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Treatment 2: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Bacterial meningitis

Irrespective of gender only Newborns (0 - 40 days old) , Infants (40 days - 1 year old) , Children (1 year - 12 years old)

Acute Meningitis in case of gram-negative microorganisms in combination with another suitable antibiotic.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Treatment 2: Intravenous - 50-200 mg/kg in 2-4 divided doses daily

Infections of genitourinary system

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 2-12 g in 2-4 divided doses daily

Treatment 2: Intramuscular - 2-12 g in 2-4 divided doses daily

Intra-abdominal infections

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 2-12 g in 2-4 divided doses daily

Treatment 2: Intramuscular - 2-12 g in 2-4 divided doses daily

Gonorrhea

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 0.5 g once

Treatment 2: Intramuscular - 0.5 g once

Peri-operative prophylaxis in colorectal, gastrointestinal, prostatic, urogenital, gynaecological surgery

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

Peri-operative prophylaxis in surgical procedures such as colorectal, gastrointestinal, prostatic, urogenital and gynaecological surgery in patients who have a definite risk of post-operative infections. Cefotaxime should be used in combination with another antibiotic that can provide anaerobic cover in the treatment of intra-abdominal infections. Cefotaxime should be used in combination with an aminoglycoside in the treatment of infections caused by Pseudomonas. Protection is best insured by achieving adequate local tissue concentrations at the time contamination is likely to occur. Administration should usually be stopped within 24 hours since continuing use of any antibiotic in the majority of surgical procedures does not reduce the incidence of subsequent infection.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 1-2 g once

Treatment 2: Intramuscular - 1-2 g once

Lyme borreliosis

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 6 g in 3 divided doses daily

Infections of the lower respiratory tract

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 2-12 g in 2-4 divided doses daily

Treatment 2: Intramuscular - 2-12 g in 2-4 divided doses daily

Endocarditis

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 2-12 g in 2-4 divided doses daily

Treatment 2: Intramuscular - 2-12 g in 2-4 divided doses daily

Sepsis

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 2-12 g in 2-4 divided doses daily

Treatment 2: Intramuscular - 2-12 g in 2-4 divided doses daily

Bacterial meningitis

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

Acute Meningitis in case of gram-negative microorganisms in combination with another suitable antibiotic.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 2-12 g in 2-4 divided doses daily

Treatment 2: Intramuscular - 2-12 g in 2-4 divided doses daily

Contraindications

Active ingredient Cefotaxime is contraindicated in the following cases: