Buspirone

Buspirone hydrochloride

Therapeutic Indications

Buspirone is indicated for:

Anxiety disorders

Irrespective of gender only Adults (18 years old or older)

Buspirone is indicated for the treatment of short-term management of anxiety disorders and the relief of symptoms of anxiety with or without accompanying symptoms of depression.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Oral - 15-60mg in three equal divided doses

Contraindications

Active ingredient Buspirone is contraindicated in the following cases:

Severe renal impairment

No gender/age discrimination

A single administration to anuretic patients causes an increase in the blood levels of the metabolite 1-pyrimidine/piperazine (1-PP), in which dialysis did not prove to have any influence on the buspirone levels, neither on the 1-PP levels. Buspirone should not be administered to patients with a creatinin clearance <20 ml/min/1.72 mĀ²), especially not to anuretic patients, because of the fact that increased and untreated levels of buspirone and its metabolites may occur.

Severe hepatic impairment

No gender/age discrimination

Acute alcoholic intoxication

No gender/age discrimination

Hypnotic intoxication

No gender/age discrimination

Acute intoxication with antipsychotic drugs

No gender/age discrimination

Epilepsy

No gender/age discrimination

Buspirone is contraindicated in patients with epilepsy.