Therapeutic Indications

Bupropion is indicated for:

Smoking cessation in nicotine-dependent patients

Irrespective of gender only Elderly (65 years old or older)

Bupropion is indicated as an aid to smoking cessation in combination with motivational support in nicotine-dependent patients.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Oral - 150mg once a day

Smoking cessation in nicotine-dependent patients

Irrespective of gender only Adults (18 - 65 years old)

Bupropion is indicated as an aid to smoking cessation in combination with motivational support in nicotine-dependent patients.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Oral - 150-300mg daily for six days

Contraindications

Active ingredient Bupropion is contraindicated in the following cases:

Monoamine oxidase inhibitors (MAOIs)

No gender/age discrimination

Concomitant use of bupropion and monoamine oxidase inhibitors (MAOIs) is contraindicated. At least 14 days should elapse between discontinuation of irreversible MAOIs and initiation of treatment with bupropion. For reversible MAOIs, a 24 hour period is sufficient.

Central nervous system (CNS) tumour

No gender/age discrimination

Bupropion is contraindicated in patients with a known central nervous system (CNS) tumour.

Seizure

No gender/age discrimination

Bupropion is contraindicated in patients with a current seizure disorder or any history of seizures.

Bipolar disorder

No gender/age discrimination

Bupropion is contraindicated in patients with a history of bipolar disorder as it may precipitate a manic episode during the depressed phase of their illness.

Severe hepatic cirrhosis

No gender/age discrimination

Bupropion is contraindicated for use in patients with severe hepatic cirrhosis.

Current or previous diagnosis of bulimia or anorexia nervosa

No gender/age discrimination

Bupropion is contraindicated in patients with a current or previous diagnosis of bulimia or anorexia nervosa.