Therapeutic Indications

Bupivacaine is indicated for:

Acute pain

Irrespective of gender only Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 0.5-2.0 mg/kg

Local anaesthesia

Irrespective of gender only Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Infiltration - 0.5-2.0 mg/kg

Major nerve block

Irrespective of gender only Children (1 year - 12 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Perineural - 0.5-2.0 mg/kg

Lumbar epidural anaesthesia for caesarean section

Women only, only Adults (18 - 65 years old)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 75-150 mg

Lumbar epidural anaesthesia

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 75-150 mg

Acute pain

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 6-37.5 mg

Treatment 2: Intra-articular - 5-100 mg

Treatment 3: Infiltration - 5-150 mg

Thoracic epidural anaesthesia

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 12.5-50 mg

Local anaesthesia

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Infiltration - 50-150 mg

Caudal epidural block

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 50-150 mg

Major nerve block

Irrespective of gender only Adolescents (12 years - 18 years old) Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Peridural - 5-175 mg

Contraindications

Active ingredient Bupivacaine is contraindicated in the following cases:

Active disease of the central nervous system

No gender/age discrimination

Active disease of the central nervous system such as meningitis, poliomyelitis, intracranial haemorrhage, sub-acute combined degeneration of the cord due to pernicious anaemia and cerebral and spinal tumours; tuberculosis of the spine;

Hypersensitivity to bupivacaine

No gender/age discrimination

Bupivacaine hydrochloride solutions are contra-indicated in patients with hypersensitivity to local anaesthetic agents of the amide type.

Intravenous regional anaesthesia (Bier's-block)

No gender/age discrimination

Solutions of bupivacaine hydrochloride are contra-indicated for intravenous regional anaesthesia (Bier’s-block).

Coagulation disorders, ongoing anticoagulation treatment

No gender/age discrimination

Pyogenic infection of the skin

No gender/age discrimination

Pyogenic infection of the skin at or adjacent to the site of lumbar puncture.

Cardiogenic shock, hypovolaemic shock

No gender/age discrimination