Therapeutic Indications

Atosiban is indicated for:

Pre-term birth

Women only, only Adults (18 - 65 years old)

Atosiban is indicated to delay imminent pre-term birth in pregnant women with:

  • regular uterine contractions of at least 30 seconds duration at a rate of ≥ 4 per 30 minutes
  • a cervical dilation of 1 to 3 cm (0-3 for nulliparas) and effacement of ≥ 50%
  • age ≥ 18 years
  • a gestational age from 24 until 33 completed weeks
  • a normal fetal heart rate.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 6.75-270 mg in 3 doses

Contraindications

Active ingredient Atosiban is contraindicated in the following cases:

Eclampsia, severe pre-eclampsia requiring delivery

No gender/age discrimination

Intrauterine foetal death

No gender/age discrimination

Suspected intrauterine infection

No gender/age discrimination

Abnormal foetal heart rate

No gender/age discrimination

Premature rupture of the membranes >30 weeks of gestation

No gender/age discrimination

Antepartum uterine haemorrhage requiring immediate delivery

No gender/age discrimination

Placenta praevia

No gender/age discrimination

Abruptio placenta

No gender/age discrimination