Arsenic trioxide

Arsenic Sesquioxide Arsenic Oxidearsenous Trioxide

Pregnancy

Arsenic trioxide has been shown to be embryotoxic and teratogenic in animal studies. There are no studies in pregnant women using arsenic trioxide. If this medicinal product is used during pregnancy or if the patient becomes pregnant while taking this product, the patient must be informed of the potential harm to the foetus.

Nursing Mothers

Arsenic is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from arsenic trioxide, breastfeeding must be discontinued prior to and throughout administration.

Carcinogenesis, Mutagenesis and Fertility

Contraception in males and females

Women of childbearing potential and men must use effective contraception during treatment with arsenic trioxide.

Fertility

No clinical or non-clinical fertility studies have been conducted with arsenic trioxide.

Effects on Ability to Drive and Use Machines

Arsenic trioxide has no or negligible influence on the ability to drive and use machines.