ATC Group: R01AC Antiallergic agents, excl. corticosteroids

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Antiallergic agents, excl. corticosteroids

Hierarchical Position

Level
Code
Title
4
R01AC
Antiallergic agents, excl. corticosteroids

Contents

Code
Title
R01AC02
R01AC03
R01AC04
R01AC05
R01AC06
R01AC07
R01AC08

Active Ingredients

Chemical substance
Description

Azelastine, a phthalazinone derivative is classified as a potent long-acting anti-allergic compound with selective H1 antagonist properties. An additional anti-inflammatory effect could be detected after topical ocular administration. Data from in vivo (pre-clinical) and in vitro studies show that azelastine inhibits the synthesis or release of the chemical mediators known to be involved in early and late stage allergic reactions e.g. leukotriene, histamine, PAF and serotonin.

Sodium cromoglicate (Cromoglicic acid) inhibits the activation of many of the cell types involved in the development and progression of asthma. Thus, sodium cromoglicate inhibits the release of inflammatory mediators including cytokines from mast cells and reduces the chemotactic activity of eosinophils and neutrophils.

Levocabastine is a potent, fast-acting and highly selective histamine H1-antagonist with a sustained duration of action.

Olopatadine is a potent selective antiallergic/antihistaminic agent that exerts its effects through multiple distinct mechanisms of action.