ATC Group: L04AA25 Eculizumab

Anatomical Therapeutic Chemical Classification System

Translations

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Eculizumab

Hierarchical Position

Active Ingredients

Chemical substance
Description

Eculizumab is a monoclonal antibody, a terminal complement inhibitor that specifically binds to the complement protein C5 with high affinity, thereby inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9. Eculizumab preserves the early components of complement activation that are essential for opsonization of microorganisms and clearance of immune complexes.