ATC Group: L04AA10 Sirolimus

Anatomical Therapeutic Chemical Classification System

Translations

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Sirolimus

Hierarchical Position

Active Ingredients

Chemical substance
Description

Sirolimus inhibits T-cell activation induced by most stimuli, by blocking calcium-dependent and calcium-independent intracellular signal transduction. Studies demonstrated that its effects are mediated by a mechanism that is different from that of ciclosporin, tacrolimus, and other immunosuppressive agents.