ATC Group: B02AA02 Tranexamic acid

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Tranexamic acid

Hierarchical Position

Level
Code
Title
5
B02AA02
Tranexamic acid

Active Ingredients

Chemical substance
Description

Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin. Tranexamic acid is a competitive inhibitor of plasminogen activation, and at much higher concentrations, a noncompetitive inhibitor of plasmin, i.e., actions similar to aminocaproic acid. Tranexamic acid is about 10 times more potent in vitro than aminocaproic acid. Tranexamic acid binds more strongly than aminocaproic acid to both the strong and weak receptor sites of the plasminogen molecule in a ratio corresponding to the difference in potency between the compounds.