ATC Group: A16AX03 Sodium phenylbutyrate

Anatomical Therapeutic Chemical Classification System

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Sodium phenylbutyrate

Hierarchical Position

Active Ingredients

Chemical substance
Description

Sodium phenylbutyrate is a pro-drug and is rapidly metabolised to phenylacetate. Phenylacetate is a metabolically active compound that conjugates with glutamine via acetylation to form phenylacetylglutamine which is then excreted by the kidneys. On a molar basis, phenylacetylglutamine is comparable to urea (each containing 2 moles of nitrogen) and therefore provides an alternate vehicle for waste nitrogen excretion.