ATC Group: A10AE Insulins and analogues for injection, long-acting

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Insulins and analogues for injection, long-acting

Hierarchical Position

Level
Code
Title
4
A10AE
Insulins and analogues for injection, long-acting

Contents

Active Ingredients

Chemical substance
Description

The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin degludec binds specifically to the human insulin receptor and results in the same pharmacological effects as human insulin. The blood glucose-lowering effect of insulin is due to the facilitated uptake of glucose following the binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin detemir is a soluble, long-acting insulin analogue with a prolonged duration of effect used as a basal insulin.

Insulin glargine is a human insulin analogue designed to have a low solubility at neutral pH. After injection, the acidic solution is neutralised leading to formation of a precipitate from which small amounts of insulin glargine are continuously released.