ATC Group: A08AB01 Orlistat

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
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Orlistat

Hierarchical Position

Active Ingredients

Chemical substance
Description

Orlistat is a potent, specific and long-acting inhibitor of gastrointestinal lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine site of the gastric and pancreatic lipases. The inactivated enzyme is thus unavailable to hydrolyse dietary fat, in the form of triglycerides, into absorbable free fatty acids and monoglycerides.