ATC Group: A08AA Centrally acting antiobesity products

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Centrally acting antiobesity products

Hierarchical Position

Contents

Code
Title
A08AA01
A08AA02
A08AA03
A08AA04
A08AA05
A08AA06
A08AA07
A08AA08
A08AA09
A08AA10
A08AA11

Active Ingredients

Chemical substance
Description

Clobenzorex is an N-substituted amphetamine analog that is converted to d-amphetamine soon after ingestion. Clobenzorex is a stimulant drug of the phenethylamine and amphetamine chemical classes used as an appetite suppressant.

Dexfenfluramine is the d-enantiomer of fenfluramine (structurally similar to amphetamine) and acts as a serotonergic anorectic drug that reduces appetite by increasing the amount of extracellular serotonin in the brain.

Mazindol is a sympathomimetic amine for the treatment of obesity and Duchenne muscular dystrophy. Like other sympathomimetic appetite suppressants, mazindol is thought to act as a reuptake inhibitor of norepinephrine. In addition, it inhibits dopamine and serotonin reuptake. It stimulates the central nervous system, which increases heart rate and blood pressure, and decreases appetite.

Mefenorex is an amphetamine derivative which was used as an appetite suppressant.

Subitramine is a potent inhibitor of monoamines (serotonin, dopamine, noradrenaline) reuptake for the treatmen of obesity. Sibutramine is metabolized to metabolites M1 and M2 which are more active toward the monoamine transporters.