ATC Group: A04AA04 Dolasetron

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Dolasetron

Hierarchical Position

Active Ingredients

Chemical substance
Description

Dolasetron and its active metabolite, hydrodolasetron (MDL 74,156), are selective serotonin 5-HT3 receptor antagonists not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors. The serotonin 5-HT3 receptors are located on the nerve terminals of the vagus in the periphery and centrally in the chemoreceptor trigger zone of the area postrema.